Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time.
Infection with hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and end-stage liver disease worldwide.The genetics of HCV infection in humans and the disease course of chronic hepatitis C are both remarkably variable.Although the response to the gel bottle audrey interferon treatment is largely dependent on